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SPONSORSHIP AVAILABLE FOR THE POSTDOCTORAL POSITION @ SHIV NADAR UNIVERSITY

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SPONSORSHIP AVAILABLE FOR THE POSTDOCTORAL POSITION

Mentor:
DEEPAK SEHGAL
PROFESSOR AND HEAD, DEPARTMENT OF LIFE SCIENCES,
SHIV NADAR UNIVERSITY,
CHITHERA, TEHSIL DADRI,
BUDH NAGAR, GREATER NOIDA: 201314

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Our Lab would like to sponsor positions for the deserving Post Doctorate Fellows (Research
Associate) who wish to apply in my lab. With me as a mentor, the project will be written by the
candidate, assisted by me for applying to the fellowships like DBT-RA, NPDF, WOS-A,B,
ICMR-RA, INSA etc. If and when the project is granted, I will be happy to accommodate the
candidate in my Lab and extend all the facilities and knowledge in the fields of Molecular
Biology, Protein Chemistry and Virology. Our Lab works on following four projects

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:

  1. Development of in vitro HEV Culture system to establish the role of its enzymes and their
    inhibitors to study the replication cycle of the virus. (DST)
  2. Biochemical and Biophysical characterization of the non-structural enzymes of HEV
    involving their crystallization to find out their inhibitors that may act as putative drug
    candidates. (DBT)
  3. Study the mechanism of processing of HEV polyprotein leading to its cleavage into Nonstructural enzymes. (DST)
  4. Modelling and simulation of the non-structural enzymes to predict the active site and its
    inhibitors using virtual screening ( WOSA)
  5. Finding out cleavage sites on HEV polyprotein by mutagenizing Cysteine protease, the
    digesting enzyme
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Desirable: The candidate desirous of getting sponsored and working with us should be well
versed with techniques in the fields of Protein Biochemistry and Molecular Biology, evident
from their publications. Please send your CV and Research Statement
to deepak.sehgal@snu.edu.in If found suitable, I will get in touch subsequently for further
discussion

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Our 2020 publication:
Published: Hepatitis E Virus Cysteine Protease has Papain like Properties Validated by insilico Modelling and Cell-free Inhibition Assays Shweta Saraswat1, Meenakshi Chaudhary1,
Deepak Sehgal1*
Front. Cell. Infect. Microbiol., 23 January 2020

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Communicated 2020: Development of BacMam Induced Hepatitis E Virus Replication Model
in Hepatoma Cells to Study the Polyprotein Processing.
Viruses: Manjeet Kumar1,¶, Preeti Hooda1,¶ Madhu Khanna2
, Utkarsh Patel1
and Deepak
Sehgal1,*
Communicated 2020 Insights in E64 induced structural changes in Hepatitis E virus protease
Meenakshi Chaudhry and Deepak Sehgal

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About Shiv Nadar University:
University is located in Village Chithera, Dadri, Gautam Budh Nagar, 10 Km from Greater
NOIDA. University has made a mark in a very short time and has been selected as one of the ten
private “Institutions of Eminence” by the Government, and the formal notification is awaited. In
the NIRF (Government’s National Institutional Ranking Framework), SNU has been the youngest
institution in the ‘top 100’ Overall list, and our score has been rising steadily. In NIRF-2019, SNU
ranked 52 in the ‘University’ category. We are also among a select group of green-field institutions
in the country which were awarded the prestigious Atal Incubation Center grant by the Niti Aayog,
Government of India, in the very first round in 2017.

DBT Junior Research Fellowship Programme (DBT – JRF) – BIOTECHNOLOGY ELIGIBILITY TEST (BET – 2020)

DEPARTMENT OF BIOTECHNOLOGYMinistry of Science &Technology, Govt. of India DBT-Junior Research Fellowship (DBT-JRF) in Biotechnology (2020) BIOTECHNOLOGY ELIGIBILITY TEST (BET) 2020 Applications are invited from bonafide Indian citizens, residing in … Continue Reading DBT Junior Research Fellowship Programme (DBT – JRF) – BIOTECHNOLOGY ELIGIBILITY TEST (BET – 2020)

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March 2020
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